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A native of Germany, Charles Neidhard came to the United States as a young man, studying medicine at the University of Pennsylvania. At that time he became ill and was treated by a friend and homeopath, Dr. William Wesselhoeft. After the success of his treatment, Neidhard attended the Academy of Homeopathic Medicine in Allentown, Pennsylvania, graduating in 1837. In 1842, Oliver Wendell Holmes, Sr., a physician and graduate of Harvard University, famously wrote “Homeopathy and Its Kindred Delusions,” an attack on this then-new system of therapeutics. Neidhard responded with his defense, “An Answer to the Homeopathic Delusions of Dr. Oliver Wendell Holmes” and continued his public defense of homeopathy throughout his career. Neidhard was most well-known for his book On the Universality of the Homeopathic Law of Cure, published in1874, and he was honored for his research and writing on diphtheria and yellow fever. A charter member of the American Institute of Homeopathy, Dr. Neidhard was also an incorporator of the Homeopathic Medical College of Philadelphia in 1848 (later Hahnemann Medical College) and served on its constitution and by-laws committee, as well as its dispensary committee. He was appointed Chair of Clinical Medicine, a position he held until 1852. Neidhard edited both the American Journal of Homeopathia and later, the North American Journal of Homeopathy, though he traveled to Europe several times to learn more about the practice of homeopathy in other parts of the world.